Sirtuins in Multiple Sclerosis: The crossroad of neurodegeneration, autoimmunity and metabolism Source https://pubmed.ncbi.nlm.nih.gov/31228716/ ABSTRACT Multiple Sclerosis (MS) is a challenging and disabling condition particularly in the secondary progressive (SP)...
A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis Source https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640558/ ABSTRACT Activation of Sirtuin (silent mating type information regulation 2 homolog) 1, or...
Sirtuins and diabetes: optimizing the sweetness in the blood Source https://transmedcomms.biomedcentral.com/articles/10.1186/s41231-019-0034-7 ABSTRACT Diabetes Mellitus (DM) is a chronic disease characterized by elevated levels of glucose in the blood. With time it...
Therapeutic role of sirtuins in neurodegenerative disease Source https://pubmed.ncbi.nlm.nih.gov/18373985/ ABSTRACT The sirtuins are a family of enzymes which control diverse and vital cellular functions, including metabolism and aging. Manipulations of sirtuin...
Role of Exercise and Natural Protective Substances on Sirtuin Activation https://www.scientificarchives.com/article/role-of-exercise-and-natural-protective-substances-on-sirtuin-activation ABSTRACT Chronic diseases are the leading drivers of the nation’s $3.8 trillion...
Polyphenols and Ischemic Stroke: Insight into One of the Best Strategies for Prevention and Treatment Source https://pubmed.ncbi.nlm.nih.gov/34201106/ ABSTRACT Ischemic stroke (IS) is still among the leading causes of death and disability worldwide. The pathogenic...
Dietary and Protective Factors to Halt or Mitigate Progression of Autoimmunity, COVID-19 and Its Associated Metabolic Diseases Source https://www.mdpi.com/1422-0067/22/6/3134 ABSTRACT COVID-19 is without any doubt the worst pandemic we have faced since the H1N1 virus...